BROKAST - L KID Tablets is a combination of Montelukast & LevocetirizineDihydrochloride. Montelukast is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene CysLT1 receptor.
The cysteinylleukotrienes (LTC4, LTD4, LTE4) are potent inflammatory eicosanoids released from various cells including mast cells and eosinophils.These important pro-asthmatic mediators bind to cysteinyl leukotriene (CysLT) receptors. The CysLT type-1 (CysLT1) receptor is found in the human airway (including airway smooth muscle cells and airway macrophages) and on other pro- inflammatory cells (including eosinophils and certain myeloid stem cells).CysLTs have been correlated with the pathophysiology of asthma and allergic rhinitis.
In allergic rhinitis, CysLTs are released from the nasal mucosa after allergen exposure during both early- and late-phase reactions and are associated with symptoms of allergic rhinitis. Intranasal challenge with CysLTs has been shown to increase nasal airway resistance and symptoms of nasal obstruction. Montelukast is an orally active compound that binds with high affinity and selectivity to the CysLT1 receptor. Montelukast inhibits physiologic actions of LTD4 at the CysLT1 receptor without any agonist activity.
Levocetirizine, the R-enantiomer of cetirizine, is a potent and selective antagonist of peripheral H1-receptors.It has been demonstrated by recent studies that the treatment of AR with concomitant administration of an antileukotriene (montelukast) and an antihistamine (levocetirizine), shows significantly better symptom relief compared with the modest improvement of rhinitis symptomatology with each of the treatments alone.
Once a day, BROKAST-L KID tablet for Children in age group of 6-11 year..
Treatment of Allergic Conditions
Treatment of Common cold
Treatment of Cough and Cold
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Store below 30℃
Shelcal - HD Tablet helps to treat Calcium deficiency that leads to weak bones as the body will start using calcium from the bone. The right amount of Vitamin D, Calcium, and Phosphorus is important for building and keeping strong bones. Shelcal - HD Tablet helps to treat Calcium deficiency that leads to weak bones as the body will start using calcium from the bone. The right amount of Vitamin D, Calcium, and Phosphorus is important for building and keeping strong bones.
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